BDBM21016 CHEMBL22870::L 732138::L-732,138::L732138::N-acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester::[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate

SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=BYYQYXVAWXAYQC-IBGZPJMESA-N

Data  20 KI  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21016   

TargetSubstance-K receptor(Rattus norvegicus (Rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Rattus norvegicus (Rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed